SCHEMBL7714062

SCHEMBL7714062

[CH2]CC=CC[CH]CC=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148006 0.84
SCHEMBL148005 0.84
SCHEMBL148792 0.77
SCHEMBL6950218 0.74
SCHEMBL3344950 0.74
SCHEMBL1114099 0.73
SCHEMBL1114100 0.73
SCHEMBL148127 0.71
SCHEMBL148128 0.71
SCHEMBL1003884 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372245-B1 Plasticized bioerodible controlled delivery system INSITE VISION INCORPORATED 2002-04-16 US disclosed
EP-0676952-B1 BIOERODIBLE CONTROLLED DELIVERY SYSTEM INSITE VISION INC (US) 2000-07-12 EP disclosed
EP-0676953-B1 PLASTICIZED BIOERODIBLE CONTROLLED DELIVERY SYSTEM INSITE VISION INC (US) 1999-05-06 EP disclosed
EP-0676953-A1 PLASTICIZED BIOERODIBLE CONTROLLED DELIVERY SYSTEM INSITE VISION INCORPORATED (US) 1995-10-18 EP disclosed
EP-0676952-A1 BIOERODIBLE CONTROLLED DELIVERY SYSTEM INSITE VISION INCORPORATED (US) 1995-10-18 EP disclosed
WO-1994014417-A1 PLASTICIZED BIOERODIBLE CONTROLLED DELIVERY SYSTEM INSITE VISION INCORPORATED (US) 1994-07-07 WO disclosed
WO-1994014416-A1 BIOERODIBLE CONTROLLED DELIVERY SYSTEM INSITE VISION INCORPORATED (US) 1994-07-07 WO disclosed
US-4898928-A ACIDIC CATALYTIC REACTION OF KETALS, DIOLS, UNSATURATED DIOLS AND POLYOXYETHYLENE GLYCOL; SUSTAINED RELEASE OF THERAPEUTIC MACROMOLECULES FROM BIOERODIBLE GELS SANDOZ PHARMACEUTICALS CORP. (US) 1990-02-06 US disclosed
US-4801457-A DRUG DELIVERY SANDOZ PHARM. CORP. (US) 1989-01-31 US disclosed
EP-0052916-B1 ERODIBLE POLYMER CONTAINING EROSION RATE MODIFIER ALZA CORPORATION (US) 1985-01-02 EP disclosed
US-4346709-A Drug delivery devices comprising erodible polymer and erosion rate modifier ALZA CORPORATION (US) 1982-08-31 US disclosed
EP-0052916-A2 Erodible polymer containing erosion rate modifier ALZA CORPORATION (US) 1982-06-02 EP disclosed
US-4322323-A Erodible device comprising surfactant for modifying the rate of erosion of the device ALZA CORPORATION (US) 1982-03-30 US disclosed
US-4282201-A Pharmaceutical comprising drug and polymer ALZA CORPORATION (US) 1981-08-04 US disclosed
US-4259102-A Composition comprising useful agent such as fertilizers, housed in heterocyclic polymer ALZA CORPORATION (US) 1981-03-31 US disclosed
US-4246397-A Polymers comprising heterocyclic system ALZA CORPORATION (US) 1981-01-20 US disclosed
US-4180646-A BIOERODABLE SUSTAINED RELEASE COTAINGS ALZA CORPORATION (US) 1979-12-25 US disclosed
US-4138344-A Erodible agent releasing device comprising poly(orthoesters) and poly(orthocarbonates) ALZA CORPORATION (US) 1979-02-06 US disclosed
US-4131648-A POLYMERIC MATERIALS ALZA CORPORATION (US) 1978-12-26 US disclosed
US-4093709-A Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates) ALZA CORPORATION (US) 1978-06-06 US disclosed