Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542383 | 0.84 | AOC3 (0.60) | PLA2G7PNP | |
| SCHEMBL10618910 | 0.79 | PLA2G7 (0.71) | PLA2G7 | |
| SCHEMBL10741582 | 0.77 | PLA2G7 (0.55) | PLA2G7PNP | |
| SCHEMBL7007970 | 0.76 | PLA2G7 (1.00) | PLA2G7 | |
| SCHEMBL5206921 | 0.76 | PLA2G7 (0.49) | PLA2G7PNP | |
| SCHEMBL5202767 | 0.76 | PDE3B (0.47) | PLA2G7PNP | |
| Peldesine SCHEMBL61135 | 0.75 | PNP (1.00) | PNP | |
| SCHEMBL11359143 | 0.75 | PLA2G7 (0.53) | PLA2G7PNP | |
| SCHEMBL7012765 | 0.75 | PLA2G7 (0.53) | PLA2G7PNP | |
| Peldesine SCHEMBL29364464 | 0.75 | PNP (1.00) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6440965-B1 | Substituted pyrimidine derivatives, their preparation and their use in the treatment of neurodegenerative or neurological disorders of the central nervous system | KRENITSKY PHARMACEUTICALS, INC. | 2002-08-27 | — | — | US | disclosed |
| EP-0004793-A2 | 2-nitro aminopyrimidone derivatives, a process for their preparation and their use to prepare 2-aminopyrimidone derivatives which have histamine H2-antagonist activity | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-10-17 | — | — | EP | disclosed |