SCHEMBL7714714

SCHEMBL7714714

O=Cc1ccccc1OCBr

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.73
HPGD P15428 1/20 0.73
HTT P42858 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
PTGDR2 Q9Y5Y4 1/20 0.59
KMT2A Q03164 5/20 0.52
LMNA P02545 3/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 2/20 0.49
SRC P12931 2/20 0.48
MEN1 O00255 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
BLM P54132 2/20 0.48
THRB P10828 1/20 0.48
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.46
RECQL P46063 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1607703 0.86 ALDH1A1 (0.77) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL6914412 0.85 ALDH1A1 (1.00) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL7908486 0.84 ALDH1A1 (0.74) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL30972130 0.83 ALDH1A1 (0.79) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL5805320 0.83 ALDH1A1 (0.87) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL8372730 0.83 ALDH1A1 (0.87) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL1276592 0.83 ALDH1A1 (0.79) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL7903822 0.82 ALDH1A1 (0.71) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL10482275 0.81 ALDH1A1 (0.69) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL28518730 0.81 ALDH1A1 (0.69) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10723837-B2 Method of preparing poly(alkylene carbonate) via copolymerization of carbon dioxide/epoxide in the presence of novel complex SK INNOVATION CO., LTD. (KR) 2020-07-28 US disclosed
EP-2976348-B1 METHOD OF PREPARING POLY(ALKYLENE CARBONATE) VIA COPOLYMERIZATION OF CARBON DIOXIDE/EPOXIDE IN THE PRESENCE OF NOVEL COMPLEX SK INNOVATION CO LTD (KR) 2019-11-20 EP disclosed
US-20180290998-A1 METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2018-10-11 US disclosed
US-20180223042-A1 Method of Preparing Poly(Alkylene Carbonate) via Copolymerization of Carbon Dioxide/Epoxide in the Presence of Novel Complex SK INNOVATION CO., LTD. (KR) 2018-08-09 US disclosed
US-9969842-B2 Method of preparing poly(alkylene carbonate) via copolymerization of carbon dioxide/epoxide in the presence of novel complex SK INNOVATION CO., LTD. (KR) 2018-05-15 US disclosed
US-20170263385-A1 HYDROPHILIC CONJUGATED POLYMERS, AND METHODS OF PREPARATION AND USE THEREOF NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2017-09-14 US disclosed
US-20160304664-A1 Method of Preparing Poly(Alkylene Carbonate) via Copolymerization of Carbon Dioxide/Epoxide in the Presence of Novel Complex SK INNOVATION CO., LTD. (KR) 2016-10-20 US disclosed
EP-2976348-A1 METHOD OF PREPARING POLY(ALKYLENE CARBONATE) VIA COPOLYMERIZATION OF CARBON DIOXIDE/EPOXIDE IN THE PRESENCE OF NOVEL COMPLEX SK Innovation Co., Ltd. (KR) 2016-01-27 EP disclosed
WO-2014148825-A1 METHOD OF PREPARING POLY(ALKYLENE CARBONATE) VIA COPOLYMERIZATION OF CARBON DIOXIDE/EPOXIDE IN THE PRESENCE OF NOVEL COMPLEX SK INNOVATION CO.,LTD. (KR) 2014-09-25 WO disclosed
EP-2766344-A1 EP1 RECEPTOR LIGANDS Laboratorios Del. Dr. Esteve, S.A. (ES) 2014-08-20 EP disclosed
WO-2013037960-A1 EP1 RECEPTOR LIGANDS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2013-03-21 WO disclosed
US-6436649-B1 COMPETITIVE BINDING WITH ANTI-HAPTEN ANTIBODY IN SOLUTION CONTAINING REPORTER MOLECULE SUBSTRATE; ADDING B-LACTAMASE QUANTITATIVE ANALYSIS USING VISIBLE OR ULTRAVIOLET RADIATION LE REGION WALLONE (BE) 2002-08-20 US disclosed
EP-0088619-A2 Benzopyrans THE UPJOHN COMPANY (US) 1983-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180290998-A1 METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES GPX1, POR, MGAM ALDH1A1 180/4885HPGD 1088/4885HTT 3673/4885
US-20160304664-A1 Method of Preparing Poly(Alkylene Carbonate) via Copolymerization of Carbon Dioxide/Epoxide in the Presence of Novel Complex SMARCC2, SMARCC1, CLNS1A ALDH1A1 4404/4885HPGD 1790/4885HTT 4642/4885
US-10723837-B2 Method of preparing poly(alkylene carbonate) via copolymerization of carbon dioxide/epoxide in the presence of novel complex SMARCC2, SMARCC1, CLNS1A ALDH1A1 4404/4885HPGD 1790/4885HTT 4642/4885
US-20180223042-A1 Method of Preparing Poly(Alkylene Carbonate) via Copolymerization of Carbon Dioxide/Epoxide in the Presence of Novel Complex SMARCC2, SMARCC1, CLNS1A ALDH1A1 4404/4885HPGD 1790/4885HTT 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.