Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | TAF1 | P21675 | 1/20 | 0.30 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.30 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31721332 | 0.80 | AXL (0.36) | BRD4 | |
| SCHEMBL1722320 | 0.73 | GRM5 (0.51) | — | |
| SCHEMBL250311 | 0.72 | — | — | |
| SCHEMBL7710156 | 0.71 | GPR84 (0.37) | ADORA2AADORA1ELANE | |
| SCHEMBL6861227 | 0.71 | GRM5 (0.42) | — | |
| SCHEMBL27890594 | 0.69 | PDE3B (0.39) | — | |
| SCHEMBL23213572 | 0.68 | — | — | |
| SCHEMBL13392361 | 0.67 | GRM5 (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8080125 | 0.67 | ADORA2A (0.35) | ADORA2AADORA1ELANEDYRK1A | |
| SCHEMBL27160636 | 0.67 | ALDH2 (0.37) | DYRK1AGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369040-B1 | INCORPORATING A COMPLEMENTARY SEQUENCES FOR HERPES, PAPILLOMA AND OTHER VIRUSES | ISIS PHARMACEUTICALS, INC. | 2002-04-09 | — | — | US | disclosed |
| US-6127333-A | COMPRISING OLIGOPEPTIDES, HAVING AMINO ACID SEQUENCES THAT ARE SELECTIVELY PROTEOLYTICALLY CLEAVED BY FREE PROSTATE SPECIFIC ANTIGEN AND KNOWN CYTOTOXIC AGENTS, CHARACTERIZED BY A DIAMINE LINKER BETWEEN THE OLIGOPEPTIDE AND VINBLASTINE | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |
| US-6060592-A | Pyrimidine nucleoside compounds and oligonucleoside compounds containing same | ISIS PHARMACEUTICALS, INC. (US) | 2000-05-09 | — | — | US | disclosed |
| WO-1995024185-A1 | NOVEL PYRIMIDINE NUCLEOSIDES | ISIS PHARMACEUTICALS, INC. (US) | 1995-09-14 | — | — | WO | disclosed |