Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.65 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.56 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.56 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108166 | 0.86 | FOLH1 (0.76) | FOLH1GRM3NAALAD2KDM4ATET2 | |
| SCHEMBL29060942 | 0.83 | FOLH1 (0.73) | FOLH1GRM3NAALAD2KDM4ATET2 | |
| SCHEMBL13726298 | 0.83 | FOLH1 (0.73) | FOLH1GRM3NAALAD2KDM4ATET2 | |
| SCHEMBL27996973 | 0.83 | FOLH1 (0.73) | FOLH1GRM3NAALAD2KDM4ATET2 | |
| SCHEMBL28640 | 0.79 | FOLH1 (1.00) | FOLH1GRM3NAALAD2KDM4ATET2 | |
| SCHEMBL107884 | 0.79 | FOLH1 (0.65) | FOLH1GRM3NAALAD2KDM4ATET2 | |
| SCHEMBL1299867 | 0.77 | FOLH1 (0.62) | FOLH1GRM3NAALAD2 | |
| SCHEMBL1722576 | 0.77 | FOLH1 (0.62) | FOLH1GRM3NAALAD2 | |
| SCHEMBL4331999 | 0.77 | FOLH1 (0.62) | FOLH1GRM3NAALAD2 | |
| SCHEMBL928641 | 0.77 | FOLH1 (0.64) | FOLH1GRM3NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369101-B1 | Therapeutic method to treat herpes virus infection | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-04-09 | — | — | US | disclosed |
| WO-1998034603-A1 | USE OF BETULIN AND ANALOGS THEREOF TO TREAT HERPESVIRUS INFECTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1998-08-13 | — | — | WO | disclosed |