Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.62 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.54 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.54 |
| ▸ | CPA3 | P15088 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6632283 | 0.86 | FOLH1 (0.57) | FOLH1 | |
| SCHEMBL108166 | 0.84 | FOLH1 (0.76) | FOLH1GRM3NAALAD2 | |
| SCHEMBL29060942 | 0.81 | FOLH1 (0.73) | FOLH1GRM3NAALAD2 | |
| SCHEMBL27996973 | 0.81 | FOLH1 (0.73) | FOLH1GRM3NAALAD2 | |
| SCHEMBL13726298 | 0.81 | FOLH1 (0.73) | FOLH1GRM3NAALAD2 | |
| SCHEMBL9814887 | 0.78 | FOLH1 (0.61) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7714795 | 0.77 | FOLH1 (0.65) | FOLH1GRM3NAALAD2 | |
| SCHEMBL28640 | 0.77 | FOLH1 (1.00) | FOLH1GRM3NAALAD2 | |
| SCHEMBL107884 | 0.77 | FOLH1 (0.65) | FOLH1GRM3NAALAD2 | |
| SCHEMBL17920178 | 0.76 | FOLH1 (0.58) | FOLH1GRM3NAALAD2CPA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313207-B | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2023-02-14 | — | — | CN | disclosed |
| WO-2009138778-A1 | CYCLOPROPYL BENZAMIDE DERIVATIVES AS INTERMEDIATES FOR CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2009-11-19 | — | — | WO | disclosed |
| EP-0047470-A1 | Method for immunochemical measurement | FUJI PHOTO FILM CO., LTD. (JP) | 1982-03-17 | — | — | EP | disclosed |