Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 9/20 | 0.49 |
| ▸ | RXRB | P28702 | 8/20 | 0.46 |
| ▸ | RARB | P10826 | 10/20 | 0.45 |
| ▸ | RARG | P13631 | 10/20 | 0.45 |
| ▸ | RARA | P10276 | 7/20 | 0.45 |
| ▸ | RXRG | P48443 | 6/20 | 0.38 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9097434 | 0.81 | CYP26A1 (0.56) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL6157965 | 0.80 | RXRA (0.52) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL6157083 | 0.80 | RXRA (0.52) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL3541162 | 0.75 | RXRA (0.58) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL9586965 | 0.74 | CYP26A1 (0.58) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL19896651 | 0.72 | TAAR1 (0.39) | — | |
| SCHEMBL3175854 | 0.71 | RXRA (0.57) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL9350200 | 0.70 | RXRA (0.64) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL7871498 | 0.70 | RXRA (0.64) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL8681351 | 0.70 | RXRA (0.56) | CYP26A1CYP3A4CYP26B1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6368608-B1 | SKIN DISORDERS | CENTRE INTERNATIONAL DE RECHERCHE DERMATOLOGIQUES GALDERMA (C.I.R.D.) (FR) | 2002-04-09 | — | — | US | disclosed |