SCHEMBL7714868

SCHEMBL7714868

COCC(=O)NC(C)c1ccc(OC)cc1

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
ACACB O00763 5/20 0.62
ACACA Q13085 1/20 0.62
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
GAA P10253 1/20 0.57
LMNA P02545 2/20 0.54
HPGD P15428 2/20 0.54
TP53 P04637 1/20 0.54
MAPT P10636 1/20 0.54
MAPK1 P28482 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
CNR1 P21554 2/20 0.53
TSHR P16473 1/20 0.51
KDM4E B2RXH2 2/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C19 P33261 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13683332 1.00 ALDH1A1 (0.63) ALDH1A1ACACBACACAKMT2AMEN1
SCHEMBL15918472 0.85 CNR1 (0.68) ALDH1A1ACACBACACAKMT2AMEN1
SCHEMBL29151019 0.85 ALDH1A1 (0.65) ALDH1A1ACACBKMT2AMEN1GAA
SCHEMBL6252896 0.85 ACACB (0.56) ALDH1A1ACACBACACAKMT2AMEN1
SCHEMBL6254231 0.85 ACACB (0.56) ALDH1A1ACACBACACAKMT2AMEN1
SCHEMBL2034758 0.85 ACACB (0.58) ALDH1A1ACACBACACAKMT2AMEN1
SCHEMBL23122976 0.84 ALDH1A1 (0.68) ALDH1A1ACACBKMT2AMEN1GAA
SCHEMBL13898948 0.84 ALDH1A1 (0.63) ALDH1A1ACACBKMT2AMEN1GAA
SCHEMBL6253330 0.84 ACACB (0.55) ALDH1A1ACACBACACAKMT2AMEN1
SCHEMBL23122978 0.84 ALDH1A1 (0.68) ALDH1A1ACACBKMT2AMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240229089-A1 A process for enzymatic synthesis of amides from amines and carboxylic acids or esters XP CHEMISTRIES AB (SE) 2024-07-11 US disclosed
EP-4308714-A1 A PROCESS FOR ENZYMATIC SYNTHESIS OF AMIDES FROM AMINES AND CARBOXYLIC ACIDS OR ESTERS XP Chemistries AB (SE) 2024-01-24 EP disclosed
WO-2022229314-A1 A PROCESS FOR ENZYMATIC SYNTHESIS OF AMIDES FROM AMINES AND CARBOXYLIC ACIDS OR ESTERS XP CHEMISTRIES AB (SE) 2022-11-03 WO disclosed
US-6387692-B1 REACTING RACEMIC AMINE WITH AN ESTER IN PRESENCE OF LIPASE FROM CANDIDA ANTARTICA AND DILUNET, SEPARATING (S)-AMINE FROM ACYLATED (R)-AMINE, THEN TREATING ACYLATED (R)-AMINE WITH ACID OR BASE TO FREE (R)-AMINE BAYER AKTIENGESELLSCHAFT (DE) 2002-05-14 US disclosed