Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.51 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719364 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CNR1CNR2LPAR1LPAR3 | |
| SCHEMBL7719362 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CNR1CNR2LPAR1LPAR3 | |
| SCHEMBL7722123 | 0.93 | ALDH1A1 (0.60) | ALDH1A1CNR1CNR2LPAR1LPAR3 | |
| SCHEMBL3489664 | 0.89 | CNR1 (0.68) | ALDH1A1CNR1CNR2LPAR1LPAR3 | |
| SCHEMBL3489657 | 0.89 | CNR1 (0.68) | ALDH1A1CNR1CNR2LPAR1LPAR3 | |
| SCHEMBL3489660 | 0.89 | CNR1 (0.68) | ALDH1A1CNR1CNR2LPAR1LPAR3 | |
| SCHEMBL3490383 | 0.89 | CNR1 (0.68) | ALDH1A1CNR1CNR2LPAR1LPAR3 | |
| SCHEMBL18686267 | 0.86 | LPAR1 (0.55) | LPAR1LPAR3LPAR2USP2 | |
| SCHEMBL11321524 | 0.86 | LPAR1 (0.55) | LPAR1LPAR3LPAR2USP2 | |
| SCHEMBL16475731 | 0.86 | LPAR1 (0.55) | LPAR1LPAR3LPAR2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387395-B1 | N-[1, (1-1) -dialkyloxy] - and N- [1, (1-1) -dialkenyloxy]- alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor | EPPSTEIN DEBORAH A (US) | 2002-05-14 | — | — | US | disclosed |
| US-5622712-A | CONSISTS OF A DRUG AND A QUATERNARY AMMONIUM SALT COMPOUND AS A LIPID COMPONENT | SYNTEX (U.S.A.) INC. (US) | 1997-04-22 | — | — | US | disclosed |
| US-5550289-A | FOR DNA TRANSFECTION | SYNTEX (U.S.A.) INC. (US) | 1996-08-27 | — | — | US | disclosed |
| US-5545412-A | USING LIPOPHILIC COMPOUNDS TO TRANSFECT DNA AND FOR DRUG DELIVERY BY FORMING COMPLEXES TO PENETRATE CELLULAR MEMBRANES | SYNTEX (U.S.A.) INC. (US) | 1996-08-13 | — | — | US | disclosed |
| US-5366737-A | Drug delivery, DNA transfection | SYNTEX (U.S.A.) INC. (US) | 1994-11-22 | — | — | US | disclosed |
| US-5208036-A | Complexing a liposomal composition with a quaternary ammonium diether | SYNTEX (U.S.A.) INC. (US) | 1993-05-04 | — | — | US | disclosed |
| US-4946787-A | DOUBLE COATED LIPOSOME COMPLEX MADE UP OF POLYANION AND A LIPID | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4897355-A | LIPISOME-POLYANION COMPLEX | SYNTEX (U.S.A.) INC. (US) | 1990-01-30 | — | — | US | disclosed |