SCHEMBL7715048

SCHEMBL7715048

CCCCCCCCCCCCCCCCCCNC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)CC

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTSL P07711 3/20 0.71
CTSS P25774 3/20 0.71
CTSB P07858 2/20 0.71
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
LMNA P02545 1/20 0.65
SIRT2 Q8IXJ6 12/20 0.56
SIRT1 Q96EB6 7/20 0.56
SIRT3 Q9NTG7 6/20 0.56
ALDH1A1 P00352 1/20 0.56
HPGD P15428 1/20 0.56
CTSK P43235 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
RAB9A P51151 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25494046 1.00 CTSL (0.71) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL1977941 1.00 CTSL (0.71) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL1977017 1.00 CTSL (0.71) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL13610346 1.00 CTSL (0.71) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL12555462 1.00 CTSL (0.71) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL13870519 0.98 CTSL (0.68) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL2441307 0.97 CTSL (0.75) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL2442047 0.97 CTSL (0.75) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL2445913 0.97 CTSL (0.75) CTSLCTSSCTSBMEN1KMT2A
SCHEMBL17965152 0.97 CTSL (0.75) CTSLCTSSCTSBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6395803-B1 POLYMERIZABLE ACRYLIC MONOMER, FILLER AND AMIDE RHEOLOGICAL MODIFIER; SHRINKAGE INHIBITION, PHYSICAL PROPERTIES, WEAR RESISTANCE KERR CORPORATION 2002-05-28 US claimed
EP-2526921-B1 DENTAL RESTORATIVE MATERIAL KERR CORP (US) 2022-12-21 EP disclosed
EP-3103156-B1 GELATED IONIC LIQUID FILM-COATED SURFACES AND USES THEREOF GELION TECH PTY LTD (AU) 2019-06-12 EP disclosed
US-20190097273-A1 GELATED IONIC LIQUID FILM-COATED SURFACES AND USES THEREOF GELION TECH PTY LTD (AU) 2019-03-28 US disclosed
US-10122049-B2 Gelated ionic liquid film-coated surfaces and uses thereof GELION TECHNOLOGIES PTY LTD (AU) 2018-11-06 US disclosed
US-20180076481-A1 SOLID ELECTROLYTE COMPOSITION, MIXTURE, COMPLEXED GEL, ELECTRODE SHEET FOR ALL-SOLID STATE SECONDARY BATTERY, ALL-SOLID STATE SECONDARY BATTERY, AND METHODS FOR MANUFACTURING SOLID ELECTROLYTE COMPOSITION, COMPLEXED GEL, ELECTRODE SHEET FOR ALL-SOLID STATE SECONDARY BATTERY AND ALL-SOLID STATE SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2018-03-15 US disclosed
US-9642782-B2 Dental restorative material KERR CORPORATION (US) 2017-05-09 US disclosed
US-20160351969-A1 GELATED IONIC LIQUID FILM-COATED SURFACES AND USES THEREOF GELION TECHNOLOGIES PTY LTD (AU) 2016-12-01 US disclosed
US-20160128910-A1 DENTAL RESTORATIVE MATERIAL KERR CORPORATION 2016-05-12 US disclosed
US-9237991-B2 Dental restorative material KERR CORPORATION (US) 2016-01-19 US disclosed
US-20140371342-A1 DENTAL RESTORATIVE MATERIAL KERR CORPORATION 2014-12-18 US disclosed
US-8822564-B2 Dental restorative material KERR CORPORATION (US) 2014-09-02 US disclosed
US-20120302662-A1 DENTAL RESTORATIVE MATERIAL KERR CORPORATION (US) 2012-11-29 US disclosed
US-6395803-B1 POLYMERIZABLE ACRYLIC MONOMER, FILLER AND AMIDE RHEOLOGICAL MODIFIER; SHRINKAGE INHIBITION, PHYSICAL PROPERTIES, WEAR RESISTANCE KERR CORPORATION 2002-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160128910-A1 DENTAL RESTORATIVE MATERIAL RPP30, RPL30, RPL6 CTSL 3160/4885CTSS 3843/4885CTSB 4178/4885
US-20120302662-A1 DENTAL RESTORATIVE MATERIAL RPP30, RPL30, RPL6 CTSL 3160/4885CTSS 3843/4885CTSB 4178/4885
US-20140371342-A1 DENTAL RESTORATIVE MATERIAL RPP30, RPL30, RPL6 CTSL 3160/4885CTSS 3843/4885CTSB 4178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.