Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 16/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 16/20 | 0.56 |
| ▸ | HTR1B | P28222 | 16/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 16/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 16/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719592 | 0.96 | HTR1A (0.57) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL7722319 | 0.92 | HTR1A (0.58) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL7719557 | 0.89 | HTR1A (0.55) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL7715222 | 0.89 | HTR1A (0.53) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7722203 | 0.88 | HTR1A (0.60) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL7720143 | 0.88 | HTR1A (0.62) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7720211 | 0.88 | HTR1A (0.57) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL7718500 | 0.87 | HTR1A (0.60) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL3458036 | 0.86 | HTR1A (0.73) | HTR1AADRA1DHTR1BADRA1AADRA1B | |
| SCHEMBL7719498 | 0.86 | HTR1A (0.56) | HTR1AADRA1DHTR1BADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387912-B1 | STROKE THERAPY | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-14 | — | — | US | disclosed |