Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20436327 | 0.92 | ALDH1A1 (0.57) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL4125050 | 0.83 | KDM4E (0.49) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29512053 | 0.82 | NPC1 (0.60) | MAPTKMT2AMEN1HPGDGAA | |
| Acetic Acid SCHEMBL28608130 | 0.81 | MAPT (0.56) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL10609908 | 0.81 | KDM4E (0.54) | MAPTKDM4EALDH1A1HPGDGLA | |
| SCHEMBL4125057 | 0.81 | ALDH1A1 (0.47) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL20441471 | 0.81 | ALDH1A1 (0.47) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL1011424 | 0.80 | ALDH1A1 (0.56) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL28417103 | 0.80 | IDO1 (0.56) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6053373 | 0.79 | RXFP1 (0.46) | MAPTKMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380392-B1 | COMPLEXES | THE PENN STATE RESEARCH FOUNDATION | 2002-04-30 | — | — | US | disclosed |