⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10635955 | 0.85 | — | — | |
| Trifluoroacetamide SCHEMBL7622498 | 0.81 | CES1 (0.43) | — | |
| SCHEMBL15993915 | 0.79 | — | — | |
| SCHEMBL7716261 | 0.76 | KCNN4 (0.32) | — | |
| Trifluoroacetamide SCHEMBL142 | 0.75 | — | — | |
| SCHEMBL987302 | 0.75 | — | — | |
| Trifluoroacetamide SCHEMBL27678123 | 0.75 | LMNA (0.42) | — | |
| Trifluoroacetamide SCHEMBL7953427 | 0.72 | — | — | |
| Trifluoroacetamide SCHEMBL11793075 | 0.72 | — | — | |
| SCHEMBL5517330 | 0.72 | LMNA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436882-B | Synthesis method of asymmetric oxamide derivative | 浙江工业大学 | 2023-09-19 | — | — | CN | claimed |
| CN-114436882-A | Method for synthesizing asymmetric oxamide derivative | 浙江工业大学 | 2022-05-06 | — | — | CN | claimed |
| CN-121800796-A | Method for preparing difluoro alkylation polycyclic coumarin derivative under visible light condition | 河南工业大学 | 2026-04-07 | — | — | CN | disclosed |
| US-12509470-B2 | Antiviral heterocyclic compounds | ENANTA PHARMACEUTICALS, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| WO-2025262036-A1 | METHOD OF MANUFACTURING A PHARMACEUTICAL COMPOSITION | RNASSIST LTD (GB) | 2025-12-26 | — | — | WO | disclosed |
| CN-121135631-A | Preparation method of 2-piperidone derivative | 浙江理工大学 | 2025-12-16 | — | — | CN | disclosed |
| US-12006326-B2 | Antiviral heterocyclic compounds | ENANTA PHARMACEUTICALS, INC. (US) | 2024-06-11 | — | — | US | disclosed |
| CN-117843543-A | Preparation method of alpha, alpha-difluorobutyrolactam | 南京工业大学 | 2024-04-09 | — | — | CN | disclosed |
| EP-3827241-B1 | DISSOCIATION OF BIOLOGICAL SAMPLES | GOLDSBOROUGH ANDREW SIMON (FR) | 2024-03-13 | — | — | EP | disclosed |
| US-20240027309-A1 | SIMPLE FIXATION AND STABILISATION | RNASSIST LTD (GB) | 2024-01-25 | — | — | US | disclosed |
| CN-117003604-A | Synthesis method and flow of allyl fluoroalkyl compound | 武汉大学 | 2023-11-07 | — | — | CN | disclosed |
| WO-2015116885-A1 | MACROCYCLES WITH AROMATIC P2' GROUPS AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-08-06 | — | — | WO | disclosed |
| US-20140295404-A1 | SAMPLE FIXATION AND STABILISATION | RNASSIST LTD. (GB) | 2014-10-02 | — | — | US | disclosed |
| WO-2014131906-A1 | SAMPLE FIXATION AND STABILISATION | GOLDSBOROUGH ANDREW SIMON (FR) | 2014-09-04 | — | — | WO | disclosed |
| EP-2742049-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS | Nissan Chemical Industries, Ltd. (JP) | 2014-06-18 | — | — | EP | disclosed |
| WO-2013024895-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-02-21 | — | — | WO | disclosed |
| CN-102796006-A | Synthesis method for 2-bromo-2,2-difluoroethylamine hydrochloride | TIANJIN TE AN CHEMTECH CO LTD | 2012-11-28 | — | — | CN | disclosed |
| US-6376710-B2 | INSECTICIDES, NEMATODICIDES, MITICIDES | SUMITOMO CHEMICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-20010041740-A1 | Amidine compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-11-15 | — | — | US | disclosed |
| EP-1138668-A2 | Amidine compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-10-04 | — | — | EP | disclosed |