Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716161 | 0.90 | MAPT (0.36) | MEN1MAPTKMT2ANPSR1PDE4B | |
| SCHEMBL7715514 | 0.81 | MEN1 (0.32) | MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL7715511 | 0.80 | ELANE (0.37) | MEN1MAPTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL7715515 | 0.80 | ELANE (0.37) | MEN1MAPTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL7715530 | 0.79 | ACP1 (0.32) | PDE4B | |
| SCHEMBL7716478 | 0.76 | KDM4E (0.33) | MEN1MAPTKMT2ASLC2A1ALDH1A1 | |
| SCHEMBL7715504 | 0.71 | ITGB1 (0.41) | — | |
| SCHEMBL7715509 | 0.71 | ITGB1 (0.41) | — | |
| SCHEMBL7715506 | 0.71 | ITGB1 (0.41) | — | |
| SCHEMBL7718454 | 0.71 | ITGB1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |