Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718431 | 0.89 | SLC8A1 (0.33) | ITGB3ITGA2BADAM17PPARGSLC8A1 | |
| SCHEMBL7714164 | 0.89 | ACACB (0.34) | ITGB3ITGA2BPPARGSLC8A1KMT2A | |
| SCHEMBL7716472 | 0.82 | ELANE (0.36) | KDM4EALDH1A1POLBP2RX3MAPT | |
| SCHEMBL7716475 | 0.82 | ELANE (0.36) | KDM4EALDH1A1POLBP2RX3MAPT | |
| SCHEMBL7264638 | 0.80 | P2RX7 (0.30) | — | |
| SCHEMBL7716473 | 0.79 | TRPV1 (0.33) | KDM4EALDH1A1POLBHCRTR2MEN1 | |
| SCHEMBL7710677 | 0.73 | KMT2A (0.34) | KDM4EALDH1A1POLBPPARGP2RX3 | |
| SCHEMBL7718441 | 0.73 | ADRA2A (0.33) | KDM4EALDH1A1P2RX3MEN1KMT2A | |
| SCHEMBL7718428 | 0.72 | ITGB1 (0.37) | PPARG | |
| SCHEMBL7718420 | 0.72 | ITGB1 (0.37) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |