Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | AXL | P30530 | 1/20 | 0.54 |
| ▸ | TYMS | P04818 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL741856 | 0.86 | AXL (0.59) | KDM4EHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL2432923 | 0.79 | KDM4E (0.60) | KDM4EHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL824649 | 0.78 | KDM4E (0.63) | KDM4EHSD17B10LMNAALDH1A1GAA | |
| SCHEMBL19953423 | 0.78 | LOXL2 (0.59) | KDM4EHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL29853659 | 0.76 | PARP15 (0.58) | KDM4EHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL26785799 | 0.76 | PARP15 (0.58) | KDM4EHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL1719777 | 0.75 | GAA (0.59) | KDM4ELMNAHPGDGAATYMS | |
| SCHEMBL13118309 | 0.75 | KDM4E (0.59) | KDM4EALDH1A1HPGDGAATYMS | |
| SCHEMBL29914786 | 0.75 | KDM4E (0.59) | KDM4EGAATYMSTNKS2TUBB4A | |
| SCHEMBL13118310 | 0.75 | KDM4E (0.59) | KDM4EALDH1A1HPGDGAATYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |