SCHEMBL7715574

SCHEMBL7715574

NC(=N/N=C/c1ccc([N+](=O)[O-])cc1)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 3/20 0.68
GRIN3B O60391 3/20 0.68
GRIN1 Q05586 3/20 0.68
GRIN2A Q12879 3/20 0.68
GRIN2B Q13224 3/20 0.68
GRIN2C Q14957 3/20 0.68
GRIN3A Q8TCU5 3/20 0.68
MAPT P10636 5/20 0.59
NPC1 O15118 4/20 0.59
RAB9A P51151 4/20 0.59
ALDH1A1 P00352 4/20 0.59
TDP1 Q9NUW8 2/20 0.59
KDM4E B2RXH2 2/20 0.59
CYP1A2 P05177 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
CASP3 P42574 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7715576 1.00 GRIN2D (0.68) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7715572 1.00 GRIN2D (0.68) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7711771 0.82 MAPT (0.63) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL29750405 0.82 GRIN2D (1.00) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL15583383 0.81 GRIN2D (0.68) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11686964 0.80 MEN1 (0.72) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3014093 0.75 BCHE (0.57) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL31005085 0.74 IKBKB (0.73) MAPTNPC1RAB9AALDH1A1TDP1
SCHEMBL4869749 0.74 PLAU (0.64) MAPTNPC1RAB9AALDH1A1MEN1
Nitric Acid SCHEMBL5575102 0.72 GRIN2D (0.76) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6379655-B1 FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION SOCIETE L'OREAL S.A. (FR) 2002-04-30 US claimed
US-6379655-B1 FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION SOCIETE L'OREAL S.A. (FR) 2002-04-30 US disclosed