Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25800531 | 0.76 | KDM4E (0.62) | DPP4KDM4ELMNAMAPK1CDC7 | |
| SCHEMBL17781089 | 0.74 | KDM4E (0.61) | DPP4KDM4ELMNAMAPK1L3MBTL1 | |
| SCHEMBL17781143 | 0.73 | KDM4E (0.57) | DPP4KDM4ELMNAMAPK1L3MBTL1 | |
| SCHEMBL6272160 | 0.70 | ALDH1A1 (0.60) | DPP4KDM4ELMNAMAPK1L3MBTL1 | |
| SCHEMBL2220072 | 0.67 | KDM4E (0.58) | KDM4ELMNAMAPK1L3MBTL1MAPT | |
| SCHEMBL17808847 | 0.66 | KDM4E (0.60) | KDM4ELMNAMAPK1L3MBTL1MAPT | |
| SCHEMBL12359379 | 0.65 | TSHR (0.48) | DPP4KDM4ELMNAL3MBTL1MAPT | |
| SCHEMBL22125239 | 0.65 | KDM4E (0.54) | KDM4ELMNAMAPK1L3MBTL1MAPT | |
| SCHEMBL10473124 | 0.65 | KDM4E (0.59) | KDM4ELMNAMAPK1L3MBTL1MAPT | |
| SCHEMBL4611248 | 0.65 | KDM4E (0.61) | KDM4ELMNAMAPK1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379395-B1 | DYEING FOR HAIR DYE | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-0888109-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-PYRIMIDINEOXO COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHODS | OREAL (FR) | 2000-08-30 | — | — | EP | claimed |
| US-6179882-B1 | OXIDATION COLOR DYES | L'OREAL (FR) | 2001-01-30 | — | — | US | disclosed |