Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 8/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715542 | 0.94 | ITGB1 (0.41) | ITGB1ITGA4ELANEEGFRKDR | |
| SCHEMBL7710752 | 0.92 | ITGB1 (0.54) | ITGB1ITGA4MAPTGAAMEN1 | |
| SCHEMBL7710696 | 0.90 | ITGB1 (0.46) | ITGB1ITGA4ELANEMEN1KMT2A | |
| SCHEMBL7716204 | 0.85 | ITGB1 (0.49) | ITGB1ITGA4MAPTGAAMEN1 | |
| SCHEMBL7716169 | 0.84 | ELANE (0.40) | ITGB1ITGA4ELANEEGFRKDR | |
| SCHEMBL7716179 | 0.84 | ELANE (0.40) | ITGB1ITGA4ELANEEGFRKDR | |
| SCHEMBL7258653 | 0.83 | ITGB1 (0.56) | ITGB1ITGA4 | |
| SCHEMBL7710715 | 0.83 | ITGB1 (0.57) | ITGB1ITGA4TP53 | |
| SCHEMBL7714166 | 0.82 | ITGB1 (0.57) | ITGB1ITGA4 | |
| SCHEMBL7714171 | 0.82 | ITGB1 (0.54) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |