Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 10/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 10/20 | 0.46 |
| ▸ | NPR3 | P17342 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715545 | 0.92 | ITGB1 (0.53) | ITGB1ITGA4 | |
| SCHEMBL7716163 | 0.90 | ITGB1 (0.48) | ITGB1ITGA4MEN1KMT2AELANE | |
| SCHEMBL7710715 | 0.85 | ITGB1 (0.57) | ITGB1ITGA4TP53KDM1A | |
| SCHEMBL7716175 | 0.85 | P2RX3 (0.36) | ITGB1ITGA4NPR3MEN1KMT2A | |
| SCHEMBL7715542 | 0.84 | ITGB1 (0.41) | ITGB1ITGA4MEN1KMT2AELANE | |
| SCHEMBL7714223 | 0.83 | ITGB1 (0.55) | ITGB1ITGA4 | |
| SCHEMBL7718440 | 0.82 | MAPT (0.34) | ITGB1ITGA4NPR3MEN1KMT2A | |
| SCHEMBL7718435 | 0.82 | MAPT (0.34) | ITGB1ITGA4NPR3MEN1KMT2A | |
| SCHEMBL7710752 | 0.82 | ITGB1 (0.54) | ITGB1ITGA4NPR3MEN1KMT2A | |
| SCHEMBL7259942 | 0.80 | ITGB1 (0.55) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |