Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL744616 | 0.86 | DYRK1A (0.45) | SLC2A1ALDH1A1POLBKDM4EHSD17B10 | |
| SCHEMBL2155887 | 0.84 | CYP17A1 (0.49) | ALDH1A1POLBKDM4EHSD17B10HPGD | |
| SCHEMBL29773842 | 0.84 | CYP17A1 (0.49) | ALDH1A1POLBKDM4EHSD17B10HPGD | |
| SCHEMBL4387539 | 0.77 | POLB (0.48) | ALDH1A1POLBSMN1; SMN2CYP2A6 | |
| SCHEMBL4766668 | 0.76 | KDM4E (0.58) | ALDH1A1KDM4EHPGDSMN1; SMN2CYP17A1 | |
| SCHEMBL29923293 | 0.75 | PLAU (0.55) | ALDH1A1POLBKDM4ECYP17A1CYP11B1 | |
| SCHEMBL1526883 | 0.75 | PLAU (0.55) | ALDH1A1POLBKDM4ECYP17A1CYP11B1 | |
| SCHEMBL9941909 | 0.75 | KDM4E (0.43) | SLC2A1ALDH1A1POLBKDM4EHSD17B10 | |
| SCHEMBL19330598 | 0.74 | NPC1 (0.48) | ALDH1A1POLBKDM4ECYP17A1CYP11B1 | |
| SCHEMBL28510400 | 0.74 | BACE1 (0.50) | ALDH1A1KDM4EHSD17B10HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |