Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 18/20 | 0.63 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.63 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259114 | 0.88 | ITGB1 (0.62) | ITGB1ITGA4 | |
| SCHEMBL7710715 | 0.87 | ITGB1 (0.57) | ITGB1ITGA4PTGDRPPARG | |
| SCHEMBL7104235 | 0.84 | ITGB1 (0.66) | ITGB1ITGA4 | |
| SCHEMBL7259004 | 0.82 | ITGB1 (0.54) | ITGB1ITGA4 | |
| SCHEMBL7716443 | 0.82 | ITGB1 (0.43) | ITGB1ITGA4PTGDR | |
| SCHEMBL7716445 | 0.82 | ITGB1 (0.43) | ITGB1ITGA4PTGDR | |
| SCHEMBL7716453 | 0.82 | ITGB1 (0.43) | ITGB1ITGA4PTGDR | |
| SCHEMBL7718449 | 0.81 | ITGB1 (0.64) | ITGB1ITGA4PPARG | |
| SCHEMBL7259184 | 0.79 | ITGB1 (0.61) | ITGB1ITGA4 | |
| SCHEMBL7104070 | 0.78 | ITGB1 (0.62) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |