Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716481 | 1.00 | ACE (0.52) | ACEPTPN1ITGB3ITGA2BCTSS | |
| SCHEMBL7718445 | 0.89 | ACE (0.53) | ACEPTPN1ITGB3ITGA2BCTSS | |
| SCHEMBL7718439 | 0.89 | ACE (0.53) | ACEPTPN1ITGB3ITGA2BCTSS | |
| SCHEMBL7714215 | 0.86 | PTPN1 (0.51) | ACEPTPN1ITGB3ITGA2BCTSS | |
| SCHEMBL7714220 | 0.86 | PTPN1 (0.51) | ACEPTPN1ITGB3ITGA2BCTSS | |
| SCHEMBL7716450 | 0.84 | ACE (0.52) | ACEPTPN1ITGB3ITGA2BCTSS | |
| SCHEMBL7718419 | 0.80 | ACE (0.50) | ACEPTPN1ITGB3ITGA2BCTSS | |
| SCHEMBL3923937 | 0.80 | ACE (0.65) | ACEPTPN1ITGB3ITGA2BCTSS | |
| SCHEMBL3923929 | 0.80 | ACE (0.65) | ACEPTPN1ITGB3ITGA2BCTSS | |
| SCHEMBL3925152 | 0.80 | ACE (0.65) | ACEPTPN1ITGB3ITGA2BCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |