SCHEMBL7716573

SCHEMBL7716573

CC(C)(c1cc(C(C)(C)c2ccccc2O)cc(C(C)(C)c2ccccc2O)c1)c1ccccc1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.60
TDP1 Q9NUW8 4/20 0.60
TSHR P16473 3/20 0.60
ESR1 P03372 6/20 0.42
ESR2 Q92731 5/20 0.42
CNR1 P21554 2/20 0.41
CNR2 P34972 2/20 0.41
ALOX15 P16050 6/20 0.40
HSD17B10 Q99714 5/20 0.40
CYP3A4 P08684 4/20 0.40
LMNA P02545 2/20 0.40
NR1I2 O75469 1/20 0.40
CYP2C9 P11712 1/20 0.40
MIF P14174 1/20 0.40
TYR P14679 1/20 0.40
HTT P42858 1/20 0.40
NFE2L2 Q16236 1/20 0.40
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1347496 0.91 ALDH1A1 (0.56) ALDH1A1TDP1TSHRESR1ESR2
SCHEMBL29599956 0.91 ALDH1A1 (0.56) ALDH1A1TDP1TSHRESR1ESR2
SCHEMBL30308900 0.88 ALDH1A1 (0.62) ALDH1A1TDP1TSHRESR1ESR2
SCHEMBL5027711 0.88 ALDH1A1 (0.62) ALDH1A1TDP1TSHRESR1ESR2
SCHEMBL10903806 0.88 ALDH1A1 (0.52) ALDH1A1TDP1TSHRESR1ESR2
SCHEMBL11645702 0.86 ALDH1A1 (0.60) ALDH1A1TDP1TSHRESR1ESR2
SCHEMBL51085 0.86 ALDH1A1 (0.60) ALDH1A1TDP1TSHRESR1ESR2
Benzene SCHEMBL11421230 0.86 ALDH1A1 (0.60) ALDH1A1TDP1TSHRESR1ESR2
SCHEMBL584830 0.85 ALDH1A1 (0.71) ALDH1A1TDP1TSHRESR1ESR2
SCHEMBL29613273 0.85 ALDH1A1 (0.71) ALDH1A1TDP1TSHRESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002356453-A NEW A,A',A\"-TRIS(HYDROXYPHENYL)-1,3,5-TRIISOPROPYLBENZENE HONSHU CHEM IND CO LTD 2002-12-13 JP disclosed