Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714623 | 0.83 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL7717028 | 0.83 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL7717224 | 0.82 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL7452392 | 0.78 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9674385 | 0.78 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL2570374 | 0.74 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL9636913 | 0.74 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL1004347 | 0.73 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL19025914 | 0.72 | CYSLTR1 (0.44) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL10694503 | 0.72 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376512-B1 | FOR TREATING PHYSIOLOGICAL CONDITION IN PATIENT WHEREIN SAID CONDITION IS ASSOCIATED WITH A PHYSIOLOGICALLY DETRIMENTAL LEVELS OF INSULIN, GLUCOSE, FREE FATTY ACIDS, OR TRIGLYCERIDES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-23 | — | — | US | disclosed |