Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3360508 | 0.99 | DPP4 (0.56) | DPP4HPGDGAARXFP1HTT | |
| SCHEMBL3363889 | 0.85 | DPP4 (0.59) | DPP4HPGDGAARXFP1HTT | |
| SCHEMBL3362127 | 0.83 | DPP4 (0.60) | DPP4RXFP1 | |
| SCHEMBL3362038 | 0.82 | DPP4 (0.57) | DPP4HPGDRXFP1HTTMAPT | |
| Hydrochloric Acid SCHEMBL3361829 | 0.82 | DPP4 (0.61) | DPP4RXFP1 | |
| SCHEMBL3361175 | 0.81 | HPGD (0.44) | DPP4HPGDGAARXFP1HTT | |
| SCHEMBL3360594 | 0.78 | DPP4 (0.71) | DPP4 | |
| SCHEMBL3363205 | 0.76 | DPP4 (0.56) | DPP4HPGDGAAHTT | |
| SCHEMBL27655116 | 0.75 | DPP4 (0.50) | DPP4MAPTKMT2A | |
| SCHEMBL3361000 | 0.75 | DPP4 (0.61) | DPP4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |