Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363205 | 0.91 | DPP4 (0.56) | DPP4HPGDGAAHTTMAPK1 | |
| Hydrochloric Acid SCHEMBL3366027 | 0.90 | DPP4 (0.56) | DPP4HPGDGAAHTTMAPK1 | |
| SCHEMBL3361355 | 0.88 | DPP4 (0.55) | DPP4ROCK2ROCK1MEN1KMT2A | |
| SCHEMBL7716792 | 0.85 | DPP4 (0.56) | DPP4HPGDGAAHTTROCK2 | |
| SCHEMBL7720962 | 0.84 | DPP4 (0.49) | DPP4GAAHTTROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL3360508 | 0.84 | DPP4 (0.56) | DPP4HPGDGAAHTTROCK2 | |
| SCHEMBL3365615 | 0.83 | DPP4 (0.41) | DPP4HPGDGAAHTTROCK2 | |
| SCHEMBL3365084 | 0.83 | DPP4 (0.57) | DPP4 | |
| Hydrochloric Acid SCHEMBL3366032 | 0.82 | DPP4 (0.58) | DPP4 | |
| Hydrochloric Acid SCHEMBL3365053 | 0.82 | DPP4 (0.55) | DPP4GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | claimed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |