Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8360050 | 0.89 | DPP4 (0.61) | DPP4KDM4EPDGFRBALDH1A1 | |
| SCHEMBL7720720 | 0.88 | DPP4 (0.59) | DPP4LMNA | |
| SCHEMBL3361967 | 0.84 | DPP4 (0.63) | DPP4PDGFRB | |
| SCHEMBL7716813 | 0.81 | DPP4 (0.53) | DPP4 | |
| SCHEMBL3363173 | 0.72 | DPP4 (0.61) | DPP4 | |
| SCHEMBL7723629 | 0.72 | DPP4 (0.48) | DPP4LMNA | |
| SCHEMBL7720666 | 0.71 | DPP4 (0.61) | DPP4 | |
| Hydrochloric Acid SCHEMBL3362783 | 0.70 | DPP4 (0.62) | DPP4 | |
| SCHEMBL3362038 | 0.69 | DPP4 (0.57) | DPP4 | |
| SCHEMBL15134832 | 0.68 | KDM4E (1.00) | KDM4ETDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |