Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716807 | 0.88 | DPP4 (0.60) | DPP4LMNA | |
| SCHEMBL8360050 | 0.86 | DPP4 (0.61) | DPP4SMN1; SMN2 | |
| SCHEMBL3361967 | 0.81 | DPP4 (0.63) | DPP4SMN1; SMN2 | |
| SCHEMBL7716813 | 0.80 | DPP4 (0.53) | DPP4 | |
| SCHEMBL3363173 | 0.72 | DPP4 (0.61) | DPP4 | |
| SCHEMBL7723629 | 0.72 | DPP4 (0.48) | DPP4SMN1; SMN2LMNARAB9A | |
| SCHEMBL7720666 | 0.71 | DPP4 (0.61) | DPP4GAA | |
| Hydrochloric Acid SCHEMBL3362783 | 0.70 | DPP4 (0.62) | DPP4GAA | |
| SCHEMBL3362038 | 0.69 | DPP4 (0.57) | DPP4SMN1; SMN2 | |
| SCHEMBL3360594 | 0.68 | DPP4 (0.71) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |