Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21588727 | 0.81 | MEN1 (0.71) | RAB9AKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL6811081 | 0.79 | CYP1A2 (0.67) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL7716934 | 0.78 | RAB9A (0.81) | RAB9AKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL6814343 | 0.78 | KMT2A (0.72) | RAB9AKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL21880903 | 0.77 | RAB9A (1.00) | RAB9AKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL11311673 | 0.76 | SMN1; SMN2 (1.00) | RAB9AKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL2183241 | 0.75 | MAPT (0.76) | RAB9AKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL7663717 | 0.74 | KDM4E (0.65) | RAB9AKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL6638013 | 0.73 | TSHR (0.73) | RAB9AKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL7161947 | 0.72 | KDM4E (0.72) | RAB9AKMT2ASMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380243-B1 | INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES- 6 AND -7, AND KAPOSI HERPESVIRUS. | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-30 | — | — | US | disclosed |