Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSH | P09668 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945567 | 0.82 | MEN1 (0.50) | KMT2AMEN1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11981379 | 0.79 | TDP1 (0.50) | KMT2AMEN1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL30543767 | 0.79 | TDP1 (0.50) | KMT2AMEN1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL18631848 | 0.79 | MEN1 (0.60) | KMT2AMEN1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11059224 | 0.77 | MEN1 (0.57) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30307374 | 0.76 | KMT2A (0.69) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL437230 | 0.76 | KMT2A (0.69) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL18095065 | 0.75 | KMT2A (0.68) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27885667 | 0.75 | KMT2A (0.68) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7461797 | 0.75 | KMT2A (0.68) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261325-A2 | NITROACRIDINE/TUMOR INHIBITOR COMPOSITIONS | NEW YORK MEDICAL COLLEGE (US) | 2002-12-04 | — | — | EP | claimed |
| WO-2001060351-A2 | NITROACRIDINE/TUMOR INHIBITOR COMPOSITIONS | NEW YORK MEDICAL COLLEGE (US) | 2001-08-23 | — | — | WO | claimed |