Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.30 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719021 | 0.90 | ALDH1A1 (0.31) | — | |
| SCHEMBL7718605 | 0.82 | MAPT (0.33) | — | |
| SCHEMBL7717193 | 0.72 | PLG (0.32) | — | |
| SCHEMBL7720030 | 0.71 | PLG (0.30) | — | |
| SCHEMBL7715784 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL7719988 | 0.71 | — | — | |
| SCHEMBL7715838 | 0.71 | — | — | |
| SCHEMBL7717214 | 0.67 | PLG (0.35) | — | |
| SCHEMBL7717201 | 0.67 | — | — | |
| SCHEMBL7715966 | 0.66 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020037534-A1 | Combinatorial preparation of a substance library with removal of a zwitterionic compound by precipitation | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-28 | — | — | US | disclosed |
| EP-1188732-A2 | Combinatorial synthesis of a chemical library involving the separation of a zwitterionic compound by precipitation | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037534-A1 | Combinatorial preparation of a substance library with removal of a zwitterionic compound by precipitation | NEFM, PSPH, NGLY1 | BACE1 607/4885HTR3E 3112/4885HTR3B 2864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.