Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 8/20 | 0.52 |
| ▸ | GAA | P10253 | 6/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | BLM | P54132 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717268 | 1.00 | MAPT (0.53) | MAPTHPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7717269 | 1.00 | MAPT (0.53) | MAPTHPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7719397 | 0.92 | MAPT (0.60) | MAPTHPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7719410 | 0.81 | NPFFR1 (0.53) | MAPTHPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7716533 | 0.80 | MAPT (0.62) | MAPTHPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7716531 | 0.80 | MAPT (0.62) | MAPTHPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7716529 | 0.80 | MAPT (0.62) | MAPTHPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7715612 | 0.79 | MAPT (0.57) | MAPTHPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7715615 | 0.79 | MAPT (0.57) | MAPTHPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7715608 | 0.79 | MAPT (0.57) | MAPTHPGDSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |