SCHEMBL7719397

SCHEMBL7719397

NC(=N/N=C/c1ccc(-c2ccccc2[N+](=O)[O-])o1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 13/20 0.60
ALDH1A1 P00352 10/20 0.60
MEN1 O00255 8/20 0.60
KMT2A Q03164 8/20 0.60
GAA P10253 6/20 0.60
MAPK1 P28482 3/20 0.60
BLM P54132 3/20 0.60
L3MBTL1 Q9Y468 2/20 0.60
KDM4E B2RXH2 2/20 0.60
PRMT5 O14744 1/20 0.60
WDR77 Q9BQA1 1/20 0.60
APAF1 O14727 1/20 0.57
HPGD P15428 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
POLB P06746 3/20 0.54
THRB P10828 2/20 0.52
TDP1 Q9NUW8 6/20 0.52
NR1I2 O75469 1/20 0.52
AHR P35869 1/20 0.52
LMNA P02545 6/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7717268 0.92 MAPT (0.53) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL7717271 0.92 MAPT (0.53) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL7717269 0.92 MAPT (0.53) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL7711771 0.81 MAPT (0.63) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL7715608 0.81 MAPT (0.57) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL7715612 0.81 MAPT (0.57) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL7715615 0.81 MAPT (0.57) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL7715539 0.79 MAPT (0.62) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL7715537 0.79 MAPT (0.62) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL7715543 0.79 MAPT (0.62) MAPTALDH1A1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6379655-B1 FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION SOCIETE L'OREAL S.A. (FR) 2002-04-30 US claimed
US-6379655-B1 FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION SOCIETE L'OREAL S.A. (FR) 2002-04-30 US disclosed