Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.72 |
| ▸ | RAB9A | P51151 | 5/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | CASP3 | P42574 | 1/20 | 0.72 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.72 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.72 |
| ▸ | PYGL | P06737 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | DHODH | Q02127 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722705 | 1.00 | NPC1 (0.72) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL30489855 | 0.98 | NPC1 (0.74) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL1702919 | 0.98 | NPC1 (0.74) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL11743614 | 0.87 | NPC1 (0.72) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL11312539 | 0.86 | NPC1 (0.62) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL392793 | 0.85 | NPC1 (0.70) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL4487883 | 0.84 | HDAC1 (0.66) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL2606255 | 0.84 | NPC1 (0.64) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL4956879 | 0.84 | NPC1 (0.69) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL1954586 | 0.84 | HDAC1 (0.66) | NPC1RAB9AKDM4ECASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081413-A2 | ONE DIMENSIONAL UNICHEMO PROTECTION (UCP) IN ORGANIC SYNTHESIS | CARLSBERG A/S (DK) | 2002-10-17 | — | — | WO | disclosed |
| US-20020146684-A1 | One dimensional unichemo protection (UCP) in organic synthesis | CARLSBERG A/S (DK) | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020146684-A1 | One dimensional unichemo protection (UCP) in organic synthesis | UMPS, UROD, URB2 | NPC1 4374/4885RAB9A 3778/4885KDM4E 1916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.