SCHEMBL7717705

SCHEMBL7717705

Cc1ccccc1-c1cccc(Nc2ccc(C=O)cc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.50
NR1H4 Q96RI1 1/20 0.43
FFAR1 O14842 3/20 0.40
NPSR1 Q6W5P4 1/20 0.40
FFAR4 Q5NUL3 2/20 0.39
HTR7 P34969 3/20 0.39
ALDH1A1 P00352 3/20 0.39
LMNA P02545 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MEN1 O00255 1/20 0.38
AR P10275 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
GAA P10253 1/20 0.38
NR4A1 P22736 1/20 0.37
F2 P00734 1/20 0.37
PLG P00747 1/20 0.37
PRSS1 P07477 1/20 0.37
MAPK13 O15264 1/20 0.37
MAPK12 P53778 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7717154 0.88 CNR1 (0.49) CNR1NR1H4FFAR1NPSR1FFAR4
SCHEMBL7716050 0.88 CNR1 (0.49) CNR1NR1H4FFAR1NPSR1FFAR4
SCHEMBL5843455 0.86 CNR1 (0.47) CNR1NR1H4FFAR1NPSR1FFAR4
SCHEMBL30232756 0.85 CNR1 (0.54) CNR1NR1H4FFAR1NPSR1FFAR4
SCHEMBL130523 0.85 CNR1 (0.54) CNR1NR1H4FFAR1NPSR1FFAR4
SCHEMBL22356061 0.84 CNR1 (0.55) CNR1NR1H4FFAR1NPSR1FFAR4
SCHEMBL5845967 0.81 CNR1 (0.50) CNR1NR1H4FFAR1NPSR1FFAR4
SCHEMBL5844799 0.78 CNR1 (0.48) CNR1NR1H4FFAR1NPSR1FFAR4
SCHEMBL12549993 0.78 ALDH1A1 (0.54) CNR1NR1H4NPSR1ALDH1A1LMNA
SCHEMBL3479559 0.78 BRD4 (0.47) CNR1NR1H4HTR7ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8197722-B2 Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2012-06-12 US disclosed
US-20020185634-A1 Two-photon or higher-order absorbing optical materials and methods of use CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-12-12 US disclosed
US-6267913-B1 IN HOLOGRAPHYL, BIOLOGY, OPTICAL DATA STORAGE CALIFORNIA INSTITUTE OF TECHNOLOGY 2001-07-31 US disclosed
WO-1998021521-A9 TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE CALIFORNIA INST OF TECHN (US) 2000-03-02 WO disclosed
WO-1998021521-A1 TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-05-22 WO disclosed