Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717761 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9ANPC1POLBGAA | |
| SCHEMBL7716557 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9ANPC1POLBGAA | |
| SCHEMBL7716552 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9ANPC1POLBGAA | |
| SCHEMBL7716554 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9ANPC1POLBGAA | |
| SCHEMBL7717772 | 0.78 | ALDH1A1 (0.38) | SMN1; SMN2RAB9ANPC1POLBMAPT | |
| SCHEMBL7717768 | 0.78 | ALDH1A1 (0.38) | SMN1; SMN2RAB9ANPC1POLBMAPT | |
| SCHEMBL7717771 | 0.78 | ALDH1A1 (0.38) | SMN1; SMN2RAB9ANPC1POLBMAPT | |
| SCHEMBL6952053 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9ANPC1POLBGAA | |
| SCHEMBL6952059 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9ANPC1POLBGAA | |
| SCHEMBL6952055 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9ANPC1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| US-6379655-B1 | FOR PROTECTION OF HUMAN SKIN AND/OR HAIR AGAINST THE DAMAGING EFFECTS OF ULTRAVIOLET IRRADIATION | SOCIETE L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |