SCHEMBL7717797

SCHEMBL7717797

CC(C)(C)[Si](Oc1cccc2c1CCC=C(COC(=O)N(c1ccccc1)c1ccccc1)C2)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 3/20 0.41
PTGER1 P34995 1/20 0.41
PTGER3 P43115 1/20 0.41
PTGDR Q13258 1/20 0.41
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7718293 0.82
SCHEMBL7776701 0.81 PTGIR (0.37) PTGIRPTGER1PTGER3PTGDRCHRM4
SCHEMBL7718289 0.80 PTGIR (0.59) PTGIRPTGER1PTGER3PTGDR
SCHEMBL7718275 0.80 PTGIR (0.36) PTGIRPTGER1PTGER3PTGDRCHRM4
SCHEMBL7772465 0.79 PTGIR (0.42) PTGIRPTGER1PTGER3PTGDR
SCHEMBL7716599 0.79 PTGIR (0.39) PTGIRPTGER1PTGER3PTGDRCHRM4
SCHEMBL7778395 0.78 PTGIR (0.67) PTGIRPTGER1PTGER3PTGDRCHRM4
SCHEMBL7776620 0.78 PTGIR (0.67) PTGIRPTGER1PTGER3PTGDRCHRM4
SCHEMBL8481589 0.78 PTGIR (0.56) PTGIRPTGER1PTGER3PTGDRCHRM4
SCHEMBL7776652 0.78 PTGIR (0.66) PTGIRPTGER1PTGER3PTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6384072-B1 CARBAMYL SUBSTITUTED COMPOUNDS WITH ETHER GROUPS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-05-07 US disclosed