Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 14/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 9/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081016 | 0.86 | PTGIR (0.40) | PTGIRPTGDRPTGER3PTGER1ATM | |
| SCHEMBL7718289 | 0.84 | PTGIR (0.59) | PTGIRPTGDRPTGER3PTGER1 | |
| SCHEMBL7717797 | 0.79 | PTGIR (0.41) | PTGIRPTGDRPTGER3PTGER1CHRM4 | |
| SCHEMBL7718281 | 0.74 | PTGIR (0.36) | PTGIRPTGDRPTGER3PTGER1ATM | |
| SCHEMBL7777424 | 0.71 | PTGIR (0.72) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7713218 | 0.70 | PTGIR (0.63) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7720294 | 0.69 | PTGIR (0.54) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL8078060 | 0.68 | PTGIR (0.40) | PTGIRPTGDRPTGER3PTGER1ATM | |
| SCHEMBL7716647 | 0.68 | PTGIR (0.50) | PTGIRPTGDRPTGER3PTGER1CHRM4 | |
| SCHEMBL7104991 | 0.66 | ATM (0.41) | PTGIRPTGDRPTGER3PTGER1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384072-B1 | CARBAMYL SUBSTITUTED COMPOUNDS WITH ETHER GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |