Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 15/20 | 0.53 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.53 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776643 | 0.94 | PTGIR (0.55) | PTGIRPTGDRPTGER3PTGER1PTGDR2 | |
| SCHEMBL7718281 | 0.84 | PTGIR (0.36) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7772443 | 0.82 | PTGIR (0.44) | PTGIRPTGDRPTGER3PTGER1KDM4E | |
| SCHEMBL8078060 | 0.79 | PTGIR (0.40) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7718275 | 0.79 | PTGIR (0.36) | PTGIRPTGDRPTGER3PTGER1 | |
| SCHEMBL7718289 | 0.77 | PTGIR (0.59) | PTGIRPTGDRPTGER3PTGER1RXRA | |
| SCHEMBL8487303 | 0.73 | PTGIR (0.45) | PTGIRPTGDRPTGER3PTGER1KDM4E | |
| SCHEMBL7776701 | 0.73 | PTGIR (0.37) | PTGIRPTGDRPTGER3PTGER1 | |
| SCHEMBL7778533 | 0.72 | PTGIR (0.67) | PTGIRPTGDRPTGER3PTGER1PTGDR2 | |
| SCHEMBL7713222 | 0.72 | PTGIR (0.89) | PTGIRPTGDRPTGER3PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384072-B1 | CARBAMYL SUBSTITUTED COMPOUNDS WITH ETHER GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-1030834-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024397-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-20 | — | — | WO | disclosed |