Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 14/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 9/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718281 | 0.83 | PTGIR (0.36) | PTGIRPTGDRPTGER3PTGER1ATM | |
| SCHEMBL7717811 | 0.79 | PTGIR (0.53) | PTGIRPTGDRPTGER3PTGER1TDP1 | |
| SCHEMBL7718275 | 0.74 | PTGIR (0.36) | PTGIRPTGDRPTGER3PTGER1CHRM4 | |
| SCHEMBL7776643 | 0.74 | PTGIR (0.55) | PTGIRPTGDRPTGER3PTGER1TDP1 | |
| SCHEMBL8081016 | 0.73 | PTGIR (0.40) | PTGIRPTGDRPTGER3PTGER1ATM | |
| SCHEMBL14181692 | 0.71 | ALDH1A1 (0.46) | TDP1 | |
| SCHEMBL7772443 | 0.70 | PTGIR (0.44) | PTGIRPTGDRPTGER3PTGER1NPSR1 | |
| SCHEMBL17092997 | 0.69 | ATM (0.53) | PTGIRPTGDRPTGER3PTGER1ATM | |
| SCHEMBL9680281 | 0.69 | ALDH1A1 (0.55) | PTGIRPTGDRATMTDP1L3MBTL1 | |
| SCHEMBL6756729 | 0.68 | MAOA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030834-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024397-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-20 | — | — | WO | disclosed |