Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 5/20 | 0.34 |
| ▸ | THRA | P10827 | 4/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23621178 | 0.76 | MEN1 (0.48) | MEN1TTRALBKMT2ACYP1A2 | |
| SCHEMBL7715334 | 0.76 | MEN1 (0.42) | MEN1TTRALBKMT2ACYP1A2 | |
| SCHEMBL11032697 | 0.75 | TDP1 (0.49) | MEN1TTRALBKMT2ACYP1A2 | |
| SCHEMBL7715299 | 0.73 | TTR (0.42) | MEN1TTRALBKMT2ACYP1A2 | |
| SCHEMBL7718047 | 0.72 | MEN1 (0.39) | MEN1TTRALBKMT2ACYP1A2 | |
| SCHEMBL5533531 | 0.70 | HPGD (0.48) | MEN1TTRALBKMT2ATHRB | |
| SCHEMBL163129 | 0.70 | AKR1B1 (0.42) | MEN1TTRALBKMT2ACYP1A2 | |
| SCHEMBL11027338 | 0.70 | VCAM1 (0.44) | MEN1TTRALBKMT2AGPR35 | |
| SCHEMBL23621177 | 0.69 | TTR (0.48) | MEN1TTRALBKMT2ACYP1A2 | |
| SCHEMBL10763582 | 0.69 | TTR (0.47) | MEN1TTRALBKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376548-B1 | FUNGICIDES; HERBICIDES; INSECTICIDES | ROHM AND HAAS COMPANY | 2002-04-23 | — | — | US | disclosed |
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |