Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 12/20 | 0.77 |
| ▸ | ITGA4 | P13612 | 12/20 | 0.77 |
| ▸ | MME | P08473 | 8/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.48 |
| ▸ | ACE | P12821 | 6/20 | 0.48 |
| ▸ | CPA1 | P15085 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7104202 | 0.82 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL7100084 | 0.80 | ITGB1 (0.69) | ITGB1ITGA4 | |
| SCHEMBL7352287 | 0.80 | ITGB1 (0.59) | ITGB1ITGA4 | |
| SCHEMBL7352276 | 0.80 | ITGB1 (0.59) | ITGB1ITGA4 | |
| SCHEMBL7258653 | 0.80 | ITGB1 (0.56) | ITGB1ITGA4 | |
| SCHEMBL7102757 | 0.79 | ITGA4 (1.00) | ITGB1ITGA4 | |
| SCHEMBL7718508 | 0.79 | ITGB1 (0.77) | ITGB1ITGA4MMEACE2ACE | |
| SCHEMBL7104336 | 0.79 | ITGB1 (0.60) | ITGB1ITGA4 | |
| SCHEMBL7099956 | 0.79 | ITGB1 (0.57) | ITGB1ITGA4 | |
| SCHEMBL7105579 | 0.79 | ITGB1 (0.60) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455539-B2 | AUTOIMMUNE DISEASE; ANTIINFLAMMATORY AGENTS; ANTIPROLIFERATORY AGENTS | CELLTECH R&D LIMITED (GB) | 2002-09-24 | — | — | US | disclosed |