Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.65 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | C1S | P09871 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718442 | 0.92 | F2 (0.60) | F2PPARGPPARDF10NR4A2 | |
| SCHEMBL7718505 | 0.92 | F2 (0.61) | F2PPARGPPARDF10ITGB3 | |
| SCHEMBL7719450 | 0.88 | F2 (0.61) | F2F10NR4A2PRSS1 | |
| SCHEMBL7454072 | 0.88 | F2 (0.66) | F2F10NR4A2MRGPRX4PRSS1 | |
| SCHEMBL7454069 | 0.86 | F2 (0.70) | F2F10NR4A2MRGPRX4PRSS1 | |
| SCHEMBL7120282 | 0.83 | PRSS1 (0.66) | F2F10ITGB3ITGA2BPRSS1 | |
| SCHEMBL7453459 | 0.83 | F2 (0.62) | F2F10NR4A2MRGPRX4PRSS1 | |
| SCHEMBL7450278 | 0.82 | F2 (0.72) | F2F10NR4A2PRSS1 | |
| SCHEMBL7452930 | 0.82 | F2 (0.94) | F2F10NR4A2PRSS1 | |
| SCHEMBL7670816 | 0.81 | F10 (0.67) | F2F10NR4A2MRGPRX4PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380430-B1 | ANTICOAGULANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTERHAFTUNG (DE) | 2002-04-30 | — | — | US | disclosed |