Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL427972 | 0.86 | BACE1 (0.60) | BACE1CTSD | |
| SCHEMBL430438 | 0.85 | BACE1 (0.62) | BACE1CTSD | |
| SCHEMBL429254 | 0.84 | BACE1 (0.77) | BACE1CTSD | |
| SCHEMBL7719982 | 0.83 | BACE1 (0.57) | BACE1CTSD | |
| SCHEMBL427949 | 0.83 | BACE1 (0.64) | BACE1CTSD | |
| SCHEMBL429075 | 0.81 | CTSD (0.72) | BACE1CTSD | |
| SCHEMBL7713911 | 0.81 | CTSD (0.54) | BACE1CTSD | |
| SCHEMBL430454 | 0.81 | BACE1 (0.66) | BACE1CTSD | |
| SCHEMBL464587 | 0.81 | BACE1 (0.58) | BACE1CTSD | |
| SCHEMBL430736 | 0.78 | BACE1 (0.74) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123674-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-06 | — | — | WO | disclosed |