Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PPIB | P23284 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | PPIG | Q13427 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15621164 | 0.86 | TET2 (0.45) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL2052655 | 0.86 | GAA (0.42) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL7442333 | 0.82 | GAA (0.42) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL6860553 | 0.80 | GAA (0.52) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL7109527 | 0.80 | TSHR (0.40) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL2038375 | 0.79 | GAA (0.46) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL17694764 | 0.79 | GAA (0.50) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL1091517 | 0.78 | GAA (0.54) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL16268161 | 0.77 | GAA (0.48) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL9711618 | 0.76 | GAA (0.48) | GAAMGAMSIMGAM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399809-B1 | FROM MALONIC ACID MONOESTER AMIDE | DEGUSSA AG (DE) | 2002-06-04 | — | — | US | disclosed |