Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2052655 | 0.93 | GAA (0.42) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL7719330 | 0.82 | GAA (0.45) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL17694764 | 0.80 | GAA (0.50) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL52466 | 0.78 | CA12 (0.35) | GAACYP2C19L3MBTL1TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL16268161 | 0.78 | GAA (0.48) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL7437449 | 0.78 | GAA (0.48) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL15903847 | 0.77 | CYP1A2 (0.46) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL6050243 | 0.77 | CA12 (0.34) | L3MBTL1LMNA | |
| SCHEMBL19792256 | 0.76 | TDP1 (0.35) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL6923478 | 0.76 | GAA (0.46) | GAAMGAMSIMGAM2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |