SCHEMBL7719451

SCHEMBL7719451

Nc1ccccc1-c1ccccc1-c1ccccc1-c1c(-c2ccccc2)cccc1-c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
HSD17B10 Q99714 2/20 0.67
L3MBTL1 Q9Y468 1/20 0.56
HPGD P15428 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 1/20 0.46
NPC1 O15118 1/20 0.46
GAA P10253 1/20 0.46
RAB9A P51151 1/20 0.46
PTPRC P08575 1/20 0.45
ADORA2A P29274 2/20 0.41
SMARCA2 P51531 2/20 0.41
SMARCA4 P51532 2/20 0.41
PBRM1 Q86U86 2/20 0.41
ADORA3 P0DMS8 1/20 0.41
BRD4 O60885 1/20 0.41
NR1I2 O75469 1/20 0.41
MAP4K4 O95819 1/20 0.39
CSF1R P07333 1/20 0.39
FGFR1 P11362 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8341762 0.94 ALDH1A1 (0.64) ALDH1A1HSD17B10L3MBTL1HPGDSMN1; SMN2
SCHEMBL10608508 0.87 ALDH1A1 (0.67) ALDH1A1HSD17B10L3MBTL1HPGDSMN1; SMN2
SCHEMBL29607177 0.86 ALDH1A1 (0.80) ALDH1A1HSD17B10L3MBTL1HPGDSMN1; SMN2
SCHEMBL29413803 0.86 ALDH1A1 (0.80) ALDH1A1HSD17B10L3MBTL1HPGDSMN1; SMN2
SCHEMBL606996 0.86 ALDH1A1 (0.80) ALDH1A1HSD17B10L3MBTL1HPGDSMN1; SMN2
SCHEMBL845163 0.86 ALDH1A1 (0.80) ALDH1A1HSD17B10L3MBTL1HPGDSMN1; SMN2
SCHEMBL24839924 0.84 ALDH1A1 (0.62) ALDH1A1HSD17B10L3MBTL1HPGDSMN1; SMN2
SCHEMBL6002306 0.84 ALDH1A1 (0.62) ALDH1A1HSD17B10L3MBTL1HPGDSMN1; SMN2
SCHEMBL6003327 0.84 ALDH1A1 (0.62) ALDH1A1HSD17B10L3MBTL1HPGDSMN1; SMN2
SCHEMBL27768614 0.84 ALDH1A1 (0.70) ALDH1A1HSD17B10L3MBTL1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6387545-B1 TERTIARY AMINE SUBSTITUTED QUATERPHENYL COMPOUND FOR COMBINED HOLE-TRANSPORTING AND LIGHT-EMITTING LAYER OF BLUE COLOR ORGANIC ELECTROLUMINESCENT DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2002-05-14 US disclosed