Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 6/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7719458 | 0.99 | CDC25A (0.47) | CDC25ALPAR1LPAR3LPAR2DNM1 | |
| Iodide SCHEMBL8912933 | 0.87 | PRKD3 (0.44) | CDC25ALPAR1LPAR3LPAR2APOBEC3A | |
| SCHEMBL7718383 | 0.87 | LPAR1 (0.47) | LPAR1LPAR3LPAR2DNM1TLR2 | |
| Hydrochloric Acid SCHEMBL7719359 | 0.85 | LPAR1 (0.46) | LPAR1LPAR3LPAR2DNM1TLR2 | |
| SCHEMBL7719494 | 0.85 | LPAR1 (0.46) | LPAR1LPAR3LPAR2DNM1TLR2 | |
| Hydrochloric Acid SCHEMBL7714986 | 0.84 | LPAR1 (0.44) | LPAR1LPAR3LPAR2DNM1TLR2 | |
| Iodide SCHEMBL8912486 | 0.82 | APOBEC3A (0.47) | CDC25ALPAR1LPAR3APOBEC3AAPOBEC3G | |
| Iodide SCHEMBL8915667 | 0.82 | USP2 (0.50) | CDC25ALPAR1LPAR3LPAR2APOBEC3A | |
| Bromide SCHEMBL8913883 | 0.81 | CDC25A (0.51) | CDC25ADNM1APOBEC3AAPOBEC3G | |
| SCHEMBL10379480 | 0.75 | LPAR1 (0.39) | LPAR1LPAR3LPAR2TLR2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387395-B1 | N-[1, (1-1) -dialkyloxy] - and N- [1, (1-1) -dialkenyloxy]- alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor | EPPSTEIN DEBORAH A (US) | 2002-05-14 | — | — | US | disclosed |
| US-5622712-A | CONSISTS OF A DRUG AND A QUATERNARY AMMONIUM SALT COMPOUND AS A LIPID COMPONENT | SYNTEX (U.S.A.) INC. (US) | 1997-04-22 | — | — | US | disclosed |
| US-5550289-A | FOR DNA TRANSFECTION | SYNTEX (U.S.A.) INC. (US) | 1996-08-27 | — | — | US | disclosed |
| US-5545412-A | USING LIPOPHILIC COMPOUNDS TO TRANSFECT DNA AND FOR DRUG DELIVERY BY FORMING COMPLEXES TO PENETRATE CELLULAR MEMBRANES | SYNTEX (U.S.A.) INC. (US) | 1996-08-13 | — | — | US | disclosed |
| US-5366737-A | Drug delivery, DNA transfection | SYNTEX (U.S.A.) INC. (US) | 1994-11-22 | — | — | US | disclosed |
| US-5208036-A | Complexing a liposomal composition with a quaternary ammonium diether | SYNTEX (U.S.A.) INC. (US) | 1993-05-04 | — | — | US | disclosed |
| US-5049386-A | Drug and DNA delivery | SYNTEX (U.S.A.) INC. (US) | 1991-09-17 | — | — | US | disclosed |
| US-4946787-A | DOUBLE COATED LIPOSOME COMPLEX MADE UP OF POLYANION AND A LIPID | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4897355-A | LIPISOME-POLYANION COMPLEX | SYNTEX (U.S.A.) INC. (US) | 1990-01-30 | — | — | US | disclosed |