⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820305 | 0.79 | — | — | |
| SCHEMBL758808 | 0.78 | — | — | |
| SCHEMBL8763461 | 0.77 | PKM (0.33) | — | |
| SCHEMBL5652197 | 0.76 | — | — | |
| SCHEMBL270046 | 0.74 | — | — | |
| SCHEMBL9036102 | 0.74 | — | — | |
| SCHEMBL1768114 | 0.72 | POLB (0.32) | — | |
| SCHEMBL29678326 | 0.72 | — | — | |
| SCHEMBL8763149 | 0.72 | PKM (0.31) | — | |
| SCHEMBL9318864 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553850-B2 | Tricyclic-bridged piperidinylidene derivatives as δ-opioid modulators | JANSSEN PHARMACEUTICA NV (BG) | 2009-06-30 | — | — | US | claimed |
| US-20060030585-A1 | Tricyclic delta-opioid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-02-09 | — | — | US | claimed |
| US-4314080-A | N-Formylation of 2-amino-2-methyl-1-propanol with chloral hydrate | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1982-02-02 | — | — | US | claimed |
| EP-4638414-A1 | IMPROVED PROCESS FOR DEPROTECTION OF N-FORMYL PROTECTED AMINES | BASF SE (DE) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024132621-A1 | IMPROVED PROCESS FOR DEPROTECTION OF N-FORMYL PROTECTED AMINES | BASF SE (DE) | 2024-06-27 | — | — | WO | disclosed |
| US-20220402871-A1 | PROCESS FOR PRODUCING SUBSTITUTED AMINO ALCOHOLS | BASF SE (DE) | 2022-12-22 | — | — | US | disclosed |
| US-20220002247-A1 | Process for producing substituted amino alcohols | BASF SE (DE) | 2022-01-06 | — | — | US | disclosed |
| US-RE47493-E1 | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-07-09 | — | — | US | disclosed |
| EP-3080115-B1 | FUSED IMIDAZOLE AND PYRAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB BIOPHARMA SPRL (BE) | 2019-05-08 | — | — | EP | disclosed |
| US-20180222868-A1 | Indazole Derivatives as Modulators of TNF Activity | UCB PHARMA S.A. (BE) | 2018-08-09 | — | — | US | disclosed |
| US-9868749-B2 | Fused imidazole and pyrazole derivatives as modulators of TNF activity | UCB BIOPHARMA SPRL (BE) | 2018-01-16 | — | — | US | disclosed |
| US-5698569-A | Retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5369084-A | Isonicotinic acid derivatives and related spiro compounds with herbicidal action | JANSSEN PHARMACEUTICAL N.V. (BE) | 1994-11-29 | — | — | US | disclosed |
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |
| WO-1992009577-A1 | ISONICOTINIC ACID DERIVATIVES AND RELATED SPIRO COMPOUNDS WITH HERBICIDAL ACTION | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-06-11 | — | — | WO | disclosed |
| US-4314080-A | N-Formylation of 2-amino-2-methyl-1-propanol with chloral hydrate | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1982-02-02 | — | — | US | disclosed |
| US-4314080-A | N-Formylation of 2-amino-2-methyl-1-propanol with chloral hydrate | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1982-02-02 | — | — | US | disclosed |
| US-4234581-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1980-11-18 | — | — | US | disclosed |
| US-4159377-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4054656-A | ASTHMA, HAY FEVER, FOODS | MEAD JOHNSON & COMPANY (US) | 1977-10-18 | — | — | US | disclosed |